Crypto investors are wary of market volatility amidst Trump's comments on the Strategic Cryptocurrency Reserve and ensuing massive liquidations. Yet, some American crypto gems have already performed well and show promise for 2025. Check out our top picks!
Bitcoin, Ethereum, and major altcoins experienced heavy losses in March. However, a new category of “made in USA” cryptocurrencies is standing out. XRP, Solana, Ondo, Uniswap, and TRUMP are distinguishing themselves with strong fundamentals and growth potential in the American regulatory context.
With a market capitalization of over $430 billion, up by +2.17% in 24 hours, the Made in USA token category demonstrates impressive resilience despite market volatility.
Trading volume also surged by +45%, reaching nearly $18 billion, showcasing massive interest from institutional and retail investors this week.
According to Nansen analysts, the trend of US-made cryptos has strengthened in recent weeks, showcasing US dominance in the crypto ecosystem. Projects like Stellar, Algorand, Hedera, Avalanche, and Sui are also emerging in this category.
While Bitcoin dropped by over 10% in March, plunging the Crypto Fear and Greed Index to just 20 out of 100 a few days ago. However, the Fear & Greed index has risen with the crypto market rebound and currently stands at 45.
In this promising context, several US-origin crypto projects stand out. Here are the 5 US-made cryptocurrencies set to soar and provide exciting opportunities for investors in 2025, with the increasing involvement of the United States in the blockchain revolution.
Ripple (XRP) remains one of the most iconic US crypto projects. This is attributed to its focus on fast and cost-effective cross-border payments for financial institutions.
Backed by strong partnerships with banks and a loyal community, XRP is once again establishing itself as a key player in the market in 2025, especially after a decisive victory against the US SEC.
XRP is currently trading around $2.44, with an ideal buying range between $2.30 and $2.52, bounded by the 50 and 100-day exponential averages.
The altcoin could test a $3.00 resistance level before aiming for a price target of $3.40. The RSI and MACD technical indicators support a bullish thesis for XRP in the coming days.
Solana needs no introduction as this Layer-1 blockchain has matured significantly. Yet, it is sometimes forgotten that it is also a Made in USA innovation.
Founded in San Francisco by Anatoly Yakovenko, Solana is known as the US tech’s “Ethereum killer,” focusing on ultra-fast processing speed and low costs due to its innovative Proof of History mechanism.
The SOL token is trading at $138.71 at the time of writing, down by 18.68% over the last month. The Ethereum competitor is close to its long-term support at $115.
A move above the $150 mark could pave the way for testing the $180 resistance. The three exponential averages at 50, 100, and 200 days are key resistances for Solana in its bullish trend.
According to VanEck, Solana’s price could reach between $300 and $520 in 2025, provided the market’s bullish trend continues.
Ondo Finance stands out as a leader in “traditional” DeFi in the US. Based in New York, the startup founded by Wall Street veterans specializes in tokenizing real-world assets (RWA), starting with US government bonds.
Practically, Ondo offers products like OUSG, a tokenized fund backed by short-term US Treasury bonds, allowing DeFi users to earn a stable return guaranteed by the US government.
The token ONDO, launched in 2023, has experienced high volatility. After reaching an ATH of $2.14, it stabilized below $1 before bouncing back in late February 2025 following integration by Mastercard and listing on Binance, briefly hitting $1.10.
Currently, ONDO is trading around $0.86, down by nearly 60% from its peak. This level forms a key area, supported by the project’s strong fundamentals, including over $1 billion in TVL in its RWA coffers.
In case of an uptrend, analysts target $1.50 or even a return to $2.10 if the momentum continues in 2025.
Uniswap remains the go-to decentralized exchange (DEX) on Ethereum and its Layer 2 solutions in 2025. Founded by Hayden Adams in New York, the protocol popularized the AMM model and is governed by a DAO that manages over $1.6 billion in assets.
The project continues to innovate with forthcoming Uniswap v4 and a well-established multi-chain strategy (Polygon, Arbitrum, BNB Chain). Despite SEC scrutiny, Uniswap has not been directly targeted, reinforcing its legitimacy on US soil.
In 2025, UNI is trading around $6.8, showing a more stable than spectacular trend with a 21.88% decline over the last month. Some analysts see a potential doubling of the price by late 2025, targeting levels between $18 and $40 in a new DeFi bullish cycle.
Its future largely depends on a potential fee redistribution to UNI holders (activation of the “fee switch”) and the adoption of upcoming innovations.
Launched on January 17, 2025, the memecoin TRUMP quickly gained attention at the intersection of crypto and politics. Fueled by the media resurgence of Donald Trump, the token surged in early 2025 with a +782% increase, reaching an ATH over $75 on January 19, 2025.
However, a significant correction followed this rapid rise. The token price dropped by about 85% to stabilize around $11.
During a recent meeting, Trump expressed intentions to make the US a Bitcoin leader and confirmed the creation of a national strategic reserve in BTC, reigniting interest in the memecoin.
With a market cap exceeding $2.3 billion and significant media exposure, $TRUMP has become a crypto barometer for President Donald Trump.
While highly speculative, the token enjoys strong social media traction and could continue to ride on the political momentum.
To invest in Made in USA cryptocurrencies, it’s ideal to use a reliable and accessible exchange like WEEX. The platform allows trading various trending tokens, including those mentioned in this top list. You can trade in Spot, Copy Trading, or with leverage in Futures.
Tip: DCA (Dollar-Cost Averaging) is a solid long-term strategy, especially for tokens like XRP and Solana. As always, invest responsibly according to your risk tolerance.
2025 is shaping up to be a pivotal year for the American crypto industry. Political backing, growing regulatory clarity, and the rise of homegrown projects could make the U.S. a global hub for blockchain innovation.
From cutting-edge initiatives like Ondo Finance, to politically charged tokens like OFFICIAL TRUMP, and DeFi giants such as Uniswap and Solana, the stars and stripes are flying high over crypto this year.
While challenges remain in a globalized and highly competitive market, one thing is certain: the “Made in USA” crypto narrative is one to watch closely in 2025.
Thomas holds a BTS in computer science with a specialization in SEO and is certified in web writing and e-commerce. Passionate about blockchain technology and cryptocurrencies since 2018, he specializes in analyzing crypto market cycles. His journey into GPU mining began in 2019 with ETH before transitioning to KASPA and Alephium (ALPH).
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